Latest
industry research report on: Global Pruritus Therapeutics Market :
Industry Size, Share, Research, Reviews, Analysis, Strategies,
Demand, Growth, Segmentation, Parameters, Forecasts
Pruritus is a chronic itching
condition, which is often caused by dermatological disease conditions
including atopic dermatitis, contact dermatitis, mycoses, chickenpox
etc. Moreover, there are various underlying etiologies for pruritus,
for instance hepatogenic pruritus results from hepatitis&jaundice,
uremic pruritus results from chronic kidney diseases and dialysis,
and some forms are drug-induced pruritus.
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The
pruritus condition is an outcome of stimulation from free nerve
endings in the dermal tissue transmitted through the C-fibers and via
the spinothalamic tract in the spinal cord. This process results in
the form of pruritus or itching. Since, this condition is a symptom
of neurologic disorders, chronic renal failure, cholestasis, systemic
infections, malignancies, and endocrine disorders, or exposure to
some drugs. The diagnosis of the actual cause of pruritus requires a
meticulous assessment involving clinical examination and laboratory
investigations, which may be dermatologic, systemic, neurogenic, and
psychogenic in nature.
The
International Forum for the Study of Itch (IFSI) has proposed three
categories of pruritus skin conditions, i.e. pruritus on normal skin,
inflamed skin, or with chronic secondary scratch lesions. Since, many
patients of chronic pruritus have skin lesions in the absence of skin
diseases due to scratching or skin dryness or insect bite. Hence,
this categorization by IFSI enables a clear distinction between
disease induced and non-specific disease induced pruritus.
The
pruritus therapeutics market can be segmented based on type of drug
classes, antihistamines (e.g. doxepin, loratadine), topical
corticosteroids (e.g. clobetasol propionate), opioid receptor
antagonists (e.g. naloxone and naltrexone),topical immunomodulators
(calcineurin inhibitors such as tacrolimus, pimecrolimus),
antidepressants (e.g. selective neuroepinephrine re-uptake inhibitor
(SNRI), mirtazapine, neuroleptics (e.g. gabapentin and pregablin),
immunosuppressants (e.g. cyclosporine and azathioprine), topical
local anesthetics (e,g. pramoxine), cannabinoid receptors (e.g. he
CB2 agonist, N-palmitoylethanolamine)and others (e.g. antipruritics
such as capsaicin, salicylic acid, polidocanol, camphor, menthol
etc.) Antihistamines prevent the activation of cells by histamine,
which lead to an allergic response. Opioid receptor antagonists
influence the neurogenic component of pruritus. Similarly, topical
therapeutic formulations are also found to be extremely effective
pertaining to pruritus. Geographically, there is a global demand for
pruritus therapeutics, which is on the rise due to high prevalence of
dermatological disorders.
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The high demand for
over-the-counter topical corticosteroids has been found to be one of
the potential drivers for growth in the market. Moreover, new product
launches and a strong pipeline for pruritus therapeutics are other
key drivers for potential growth in this market. However, a major
restraint in the pruritus therapeutics market is lack of awareness of
the root cause of pruritus and a universally accepted therapy for
pruritus. Some of these factors can offset the growth of pruritus
therapeutics in the market.The key opportunities in the pruritus
therapeutics market include new discoveries such as the
identification of new T-cell subsets (Th17 & Th22), and patent
expiry of various pruritus therapeutic drugs such as Protopic
(tacrolimus). Moreover, pruritus condition covers a widerange of
potential target population, as skin disorders are extremely common
worldwide. These factors will provide a platform for new players in
the market to capitalize such avenues in the pruritus therapeutics
market.Therefore, it is anticipated that these lucrative
opportunities could contribute to the growth of pruritus therapeutics
in future.
Some of the major players that
are operating in the pruritus therapeutics market include Allergan
Inc., Amgen Inc., Astellas Pharma Inc., CARA Therapeutics, Novartis
AG, and Teva Pharmaceutical Industries Ltd.
This research report analyzes
this market on the basis of its market segments, major geographies,
and current market trends. This report provides comprehensive
analysis of
Market growth drivers
Factors limiting market
growth
Current market trends
Market structure
Market projections for
upcoming years
This report is a complete study
of current trends in the market, industry growth drivers, and
restraints. It provides market projections for the coming years. It
includes analysis of recent developments in technology, Porter’s
five force model analysis and detailed profiles of top industry
players. The report also includes a review of micro and macro factors
essential for the existing market players and new entrants along with
detailed value chain analysis.
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It provides a six-year
forecast assessed on the basis of how the market is predicted to grow
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